Managing chronic pain is one of the challenging tasks. It becomes more complicated when it arises from underlying health conditions because we need to manage the health conditions as well the pain and discomfort caused by it. It’s a smart move to buy Tapentadol 100mg online UK pills for round-the clock pain management. However, the crucial part is to be aware of the safety profile of the medicine.

In this article, we will discuss the safety profile of Tapentadol. We will also be looking at the mechanism of action of the drug, side effects caused by it, and preventive measures to minimize the discomfort caused by them.

What is Tapentadol?

It’s an opioid pain management drug that is available in the form of regular and extended-release format. This medicine reduces moderate to severe pain caused by musculoskeletal and neurological conditions. This medicine is used when non-opioid painkillers are not enough to reduce the pain. it is an atypical opioid which means it is an opioid agonist and also a norepinephrine reuptake inhibitor.

Image source: https://en.wikipedia.org/wiki/Tapentadol

Tapentadol was discovered in the 1980, and later was approved for medical usages in 2008 by the U.S. Food and Drug Administration (FDA). Though it is derived from Tramadol, this painkiller has potent opioid effects but has weaker effects on the norepinephrine reuptake process as compared to its parental medicine.

This medicine works as fast as within 30 minutes post administration, and the analgesic effect stays for about 4 to 6 hours. For a round-the-clock pain management, extended-release tablets are used.

Tapentadol Dosage Guide: How To Take The Medicine Safely For Better Results Adult dosage for musculoskeletal pain

Pain management medicines need to be taken as directed by a doctor. It is available in two forms – regular and extended-release tablets. Your doctor will decide which form of the medicine to be given as per the intensity of the pain. This medicine is available in 25mg, 50mg, 100mg, and 150mg strengths.

The initial dose is 50 or 100mg given every 4 to 6 hours, or required. The maximum dose given in a day should not exceed 700mg.

Adult dosage for neuropathic pain

The treatment starts with 50mg dosage given every 12 hours. The maximum dosage is up to 500mg a day.

The extended-release tablets are given every 12 hours to manage the pain. When a patient is shifted to extended-release formulation from regular one, he/she might experience respiratory depression and excessive sedation.

Adult dosage for chronic pain

For chronic pain, extended-release tablets are given. A 50mg dosage is given twice a day with the time window of 12 hours. This dosage can be increased up to 500mg a day depending on the

Tapentadol 100mg can also be given to children to reduce pain. However, the dosages need to be adjusted as per their body weight along with underlying health conditions which are or are not associated with the pain.

Side effects profile

You may or may not experience side effects after taking the medicine. Some people may develop a few common side effects that stay as long as your body gets accustom to the medicine. Some people may get a few severe side effects which need to be addressed medically.

Constipation, vomiting, nausea, stomach upset or pain, tiredness, dizziness, drowsiness, headache, etc are some of the commonly occurring side effects. These side effects stay for a short duration, and usually disappear.

Though it is rare to get severe side effects post taking Tapentadol 100mg tablets, it is crucial to know what these side effects are.

Shallow breathing or difficulty in breathing, severe dizziness or sleepiness, problems with speech, poor coordination, seizures, lightheadedness, etc are some of the reported side effects. If any of these side effects occur after taking the medicine; please get immediate medical help. Stop using the medicine until your doctor asks you to resume the treatment.

Tapentadol risk profile leading to Tapentadol overdose

The major risk factors that lead to Tapentadol overdose are drug abuse, relapse, and using it with other medicines or substances.

Tapentadol abuse

Consuming higher dosage frequently increases your risk of overdosing on the medicine. Taking the medicine in other ways such as crushing or dissolving it in liquids such as fruit juices or milk also put you at the risk of overdose.

Relapse

After a certain time frame, your body starts building up tolerance against the medicine. It means you may need large dosages to get the results which you used to get with the prescribed or low dosage of the medicine. However, if you stop taking the drug abruptly, the relapse could be worse as it decreases the tolerance. In simpler words, if you resume the treatment with a low dose, you may experience symptoms of overdose due to low tolerance.

Mixing the drug with other substances

Some medicines such as sedatives, antipsychotics, muscle relaxants, antidepressants, benzodiazepines, and substances like alcohol interact with the pain management drug increasing the risk of severe side effects. Also, you should never take this painkiller with other opioid medicines.

Is Tapentadol safe?

Before you buy Tapentadol 100mg online, you must know that this medicine needs to be taken strictly as directed by a doctor. As the medicine works on the CNS or central nervous system, overdosing on the medicine or taking it with any other drugs or substances should be prohibited under any circumstances.

Tapentadol is safe to consume if you are practicing the precautionary measures religiously to prevent unpleasant incidents such as overdosing.

Ref. Links

https://www.drugs.com/dosage/tapentadol.html

https://www.healthdirect.gov.au/tapentadol

https://www.thewaltoncentre.nhs.uk/patient-leaflets/tapentadol-for-chronic-pain/629719

https://www.christie.nhs.uk/media/20dpk2ol/1297-tapentadol-sup-november-2021.pdf

https://www.tandfonline.com/doi/full/10.1080/03007995.2020.1832977

https://anrclinic.com/blog/tapentadol-overdose/